Zfp251^em1Hgseo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zfp251^em1Hgseo
• Name: zinc finger protein 251; endonuclease-mediated mutation 1, Han Geuk Seo
• MGI ID: MGI:7539479
• Gene: Zfp251 Location: Chr15:76736331-76755635 bp, - strand Genetic Position: Chr15, 36.28 cM
• Alliance: Zfp251^em1Hgseo page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 4 removed the region encoding the zinc finger. (J:334395)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp251 Mutation: 24 strains or lines available

References

• Original: J:334395 Kim E, et al., Zinc finger protein 251 deficiency impairs glucose metabolism by inducing adipocyte hypertrophy. Mol Cell Endocrinol. 2022 Dec 21;562:111838
• All: 1 reference(s)