Duxf3^em1Sgao
Endonuclease-mediated Allele Detail

Summary

• Symbol: Duxf3^em1Sgao
• Name: double homeobox family member 3; endonuclease-mediated mutation 1, Shaorong Gao
• MGI ID: MGI:7539482
• Gene: Duxf3 Location: Chr10:58066473-58068497 bp, - strand Genetic Position: Chr10, 29.29 cM
• Alliance: Duxf3^em1Sgao page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of the macrosatellite tandem-array repeat region generated a null allele by deleting the region encoding the second homeobox domain. (J:328721)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Duxf3 Mutation: 7 strains or lines available

References

• Original: J:328721 Guo M, et al., Precise temporal regulation of Dux is important for embryo development. Cell Res. 2019 Nov;29(11):956-959
• All: 3 reference(s)