Taok1^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Taok1^em1Cya
• Name: TAO kinase 1; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7539703
• Synonyms: Taok1^fl
• Gene: Taok1 Location: Chr11:77419988-77498641 bp, - strand Genetic Position: Chr11, 46.64 cM, cytoband B5
• Alliance: Taok1^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 technology generated a floxed allele. Molecular information on floxed region is not provided. (J:341459)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Taok1 Mutation: 45 strains or lines available

References

• Original: J:341459 Zhang Z, et al., TAOK1 negatively regulates IL-17-mediated signaling and inflammation. Cell Mol Immunol. 2018 Aug;15(8):794-802
• All: 2 reference(s)