Tg(Myh6-TNNI3K)#Dmar
Transgene Detail

Summary

• Symbol: Tg(Myh6-TNNI3K)#Dmar
• Name: transgene insertion, Douglas A Marchuk
• MGI ID: MGI:7539752
• Synonyms: TNNI3K^tg
• Transgene: Tg(Myh6-TNNI3K)#Dmar Location: unknown
• Alliance: Tg(Myh6-TNNI3K)#Dmar page

Transgene origin

• Strain of Origin: (C57BL/6J x SJL/J)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The murine cardiac myosin alpha promoter was used to drive expression of the human TNNI3 interacting kinase cDNA (with SV40 poly(A) signal sequences). Three lines were created containing either 10-20 or >100 copies of the transgene. (J:154116)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:154116 Wheeler FC, et al., Tnni3k modifies disease progression in murine models of cardiomyopathy. PLoS Genet. 2009 Sep;5(9):e1000647
• All: 1 reference(s)