Ak9^em1Lnl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ak9^em1Lnl
• Name: adenylate kinase 9; endonuclease-mediated mutation 1, Lin Li
• MGI ID: MGI:7540710
• Gene: Ak9 Location: Chr10:41179433-41309565 bp, + strand Genetic Position: Chr10, 22.23 cM
• Alliance: Ak9^em1Lnl page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 82 bp. (J:340782)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ak9 Mutation: 65 strains or lines available

References

• Original: J:340782 Sha Y, et al., Deficiency in AK9 causes asthenozoospermia and male infertility by destabilising sperm nucleotide homeostasis. EBioMedicine. 2023 Sep 13;96:104798
• All: 1 reference(s)