St6galnac3^em1Staka
Endonuclease-mediated Allele Detail

Summary

• Symbol: St6galnac3^em1Staka
• Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; endonuclease-mediated mutation 1, Satoru Takahashi
• MGI ID: MGI:7540721
• Gene: St6galnac3 Location: Chr3:152903911-153430804 bp, - strand Genetic Position: Chr3, 77.82 cM, cytoband H4
• Alliance: St6galnac3^em1Staka page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 3. (J:340690)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any St6galnac3 Mutation: 33 strains or lines available

References

• Original: J:340690 Fuseya S, et al., Reduction in disialyl-T antigen levels in mice deficient for both St6galnac3 and St6galnac4 results in blood filling of lymph nodes. Sci Rep. 2023 Jun 29;13(1):10582
• All: 1 reference(s)