Bbof1^em1Liwe
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bbof1^em1Liwe
• Name: basal body orientation factor 1; endonuclease-mediated mutation 1, Wei Li
• MGI ID: MGI:7541199
• Gene: Bbof1 Location: Chr12:84455243-84488279 bp, + strand Genetic Position: Chr12, 39.2 cM, cytoband D3
• Alliance: Bbof1^em1Liwe page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 5 through 9. (J:339669)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bbof1 Mutation: 24 strains or lines available

References

• Original: J:339669 Liu C, et al., CCDC176 stabilizes microtubule doublets 1 and 9 to ensure proper sperm movement. Curr Biol. 2023 Aug 21;33(16):3371-3388.e7
• All: 1 reference(s)