Ttc6^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ttc6^em1Cya
• Name: tetratricopeptide repeat domain 6; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7541253
• Gene: Ttc6 Location: Chr12:57610899-57784714 bp, + strand Genetic Position: Chr12, 24.7 cM
• Alliance: Ttc6^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 through 32. (J:341550)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ttc6 Mutation: 57 strains or lines available

References

• Original: J:341550 Wang Z, et al., TTC6-Mediated Stabilization of the Flagellum Annulus Ensures the Rapid and Directed Motion of Sperm. Cells. 2023 Aug 18;12(16)
• All: 1 reference(s)