2610035D17Rik^em2Zhgn
Endonuclease-mediated Allele Detail

Summary

• Symbol: 2610035D17Rik^em2Zhgn
• Name: RIKEN cDNA 2610035D17 gene; endonuclease-mediated mutation 2, Zhang Nu
• MGI ID: MGI:7541316
• Synonyms: Rason^mut
• Gene: 2610035D17Rik Location: Chr11:112934732-113092664 bp, - strand Genetic Position: Chr11, 78.62 cM
• Alliance: 2610035D17Rik^em2Zhgn page

Mutation origin

• Strain of Origin: C57BL/6JGpt-Kras^em1Gpt Trp53^em3Gpt/Gpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Nucleotide substitutions
• CRISPR-targeting replaced the two translation sites with stop codons. (J:339253)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any 2610035D17Rik Mutation: 2 strains or lines available

References

• Original: J:339253 Cheng R, et al., A novel protein RASON encoded by a lncRNA controls oncogenic RAS signaling in KRAS mutant cancers. Cell Res. 2023 Jan;33(1):30-45
• All: 1 reference(s)