Enoph1^em1Zhgy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Enoph1^em1Zhgy
• Name: enolase-phosphatase 1; endonuclease-mediated mutation 1, Yuan Zhang
• MGI ID: MGI:7543408
• Gene: Enoph1 Location: Chr5:100187844-100216619 bp, + strand Genetic Position: Chr5, 48.46 cM
• Alliance: Enoph1^em1Zhgy page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 through 5. (J:336756)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Enoph1 Mutation: 92 strains or lines available

References

• Original: J:336756 Yang D, et al., Evidence that enolase-phosphatase 1 exacerbates early cerebral ischemia injury and blood-brain barrier breakdown by enhancing extracellular matrix destruction and inhibiting the interaction between ADI1 and MT1-MMP. Exp Neurol. 2023 Jul;365:114410
• All: 1 reference(s)