Trmt61a^em1Hbgl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trmt61a^em1Hbgl
• Name: tRNA methyltransferase 61A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7543515
• Synonyms: Trmt61a^flox
• Gene: Trmt61a Location: Chr12:111644539-111650336 bp, + strand Genetic Position: Chr12, 61.09 cM
• Alliance: Trmt61a^em1Hbgl page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting generated a conditional allele. (J:336736)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trmt61a Mutation: 34 strains or lines available

References

• Original: J:336736 Liu Y, et al., tRNA-m(1)A modification promotes T cell expansion via efficient MYC protein synthesis. Nat Immunol. 2022 Oct;23(10):1433-1444
• All: 1 reference(s)