Trmt6^em1Hbgl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trmt6^em1Hbgl
• Name: tRNA methyltransferase 6; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7543517
• Synonyms: Trmt6^flox
• Gene: Trmt6 Location: Chr2:132646127-132657975 bp, - strand Genetic Position: Chr2, 64.74 cM
• Alliance: Trmt6^em1Hbgl page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 2. (J:336736)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trmt6 Mutation: 28 strains or lines available

References

• Original: J:336736 Liu Y, et al., tRNA-m(1)A modification promotes T cell expansion via efficient MYC protein synthesis. Nat Immunol. 2022 Oct;23(10):1433-1444
• All: 1 reference(s)