Gt(ROSA)26Sortm1(Mib1*V943F)Jlp
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1(Mib1*V943F)Jlp |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Jose de la Pompa |
MGI ID: |
MGI:7543648 |
Synonyms: |
R26MIB1V943F |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1(Mib1*V943F)Jlp page
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Allele Type: |
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Targeted (Conditional ready, Inserted expressed sequence) |
Mutation: |
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Insertion
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Mutation details: The following elements were inserted in an intron of the gene: a loxP site, a neomycin resistance gene and STOP cassette, a second loxP site, sequence coding for an HA tag in-frame with the coding sequence for Mib1 with a p.V943F mutation, IRES sequence and the EGFP fluorescent reporter gene. The inserted Mib1 and EGFP genes will only be expressed after Cre-mediated removal of the neo-STOP cassette.
(J:338889)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
992 strains or lines available
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Original: |
J:338889 Siguero-Alvarez M, et al., A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65 |
All: |
1 reference(s) |
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