Mir147^tm1.2Xyn
Targeted Allele Detail

Summary

• Symbol: Mir147^tm1.2Xyn
• Name: microRNA 147; targeted mutation 1.2, Xiaoyi Yuan
• MGI ID: MGI:7544886
• Gene: Mir147 Location: Chr2:122482723-122482801 bp, + strand Genetic Position: Chr2, 60.64 cM
• Alliance: Mir147^tm1.2Xyn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:332925
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct floxed the 114 bp microRNA sequence. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. Cre-mediated recombination removed the microRNA sequence. (J:332925)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir147 Mutation: 0 strains or lines available

References

• Original: J:332925 Kim B, et al., Characterization of a Murine Model System to Study MicroRNA-147 During Inflammatory Organ Injury. Inflammation. 2021 Aug;44(4):1426-1440
• All: 1 reference(s)