Wdfy4^em1Jkln
Endonuclease-mediated Allele Detail

Summary

• Symbol: Wdfy4^em1Jkln
• Name: WD repeat and FYVE domain containing 4; endonuclease-mediated mutation 1, Justin Kline
• MGI ID: MGI:7545162
• Gene: Wdfy4 Location: Chr14:32681504-32907465 bp, - strand Genetic Position: Chr14, 19.44 cM
• Alliance: Wdfy4^em1Jkln page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed exon 4, resulting in a frame-shift mutation and premature stop codon. (J:326216)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdfy4 Mutation: 142 strains or lines available

References

• Original: J:326216 MacNabb BW, et al., Dendritic cells can prime anti-tumor CD8(+) T cell responses through major histocompatibility complex cross-dressing. Immunity. 2022 Jun 14;55(6):982-997.e8
• All: 1 reference(s)