Skint2^em2Htaka
Endonuclease-mediated Allele Detail

Summary

• Symbol: Skint2^em2Htaka
• Name: selection and upkeep of intraepithelial T cells 2; endonuclease-mediated mutation 2, Hiroshi Takayanagi
• MGI ID: MGI:7545259
• Synonyms: Skint2^delta
• Gene: Skint2 Location: Chr4:112470917-112509447 bp, + strand Genetic Position: Chr4, 51.53 cM
• Alliance: Skint2^em2Htaka page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted the first and fifth protein-coding exons (exons 2 and 6). (J:291989)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Skint2 Mutation: 29 strains or lines available

References

• Original: J:291989 Jandke A, et al., Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial gammadelta T cell compartments. Nat Commun. 2020 Jul 28;11(1):3769
• All: 1 reference(s)