Crp^em1Wuy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Crp^em1Wuy
• Name: C-reactive protein, pentraxin-related; endonuclease-mediated mutation 1, Yi Wu
• MGI ID: MGI:7545590
• Gene: Crp Location: Chr1:172525623-172527533 bp, + strand Genetic Position: Chr1, 80.13 cM
• Alliance: Crp^em1Wuy page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting inserted a STOP cassette at the translation start site. (J:341658)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crp Mutation: 18 strains or lines available

References

• Original: J:341658 Li HY, et al., C-Reactive Protein Protects Against Acetaminophen-Induced Liver Injury by Preventing Complement Overactivation. Cell Mol Gastroenterol Hepatol. 2022;13(1):289-307
• All: 2 reference(s)