Adgrf2^em1Iwto
Endonuclease-mediated Allele Detail

Summary

• Symbol: Adgrf2^em1Iwto
• Name: adhesion G protein-coupled receptor F2; endonuclease-mediated mutation 1, Tsutomu Iwamoto
• MGI ID: MGI:7545665
• Gene: Adgrf2 Location: Chr17:43007021-43053070 bp, - strand Genetic Position: Chr17, 19.66 cM
• Alliance: Adgrf2^em1Iwto page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• TALEN-targeting of exon 3 deleted 2 bp. (J:341655)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adgrf2 Mutation: 33 strains or lines available

References

• Original: J:341655 Chiba Y, et al., Deficiency of G protein-coupled receptor Gpr111/Adgrf2 causes enamel hypomineralization in mice by alteration of the expression of kallikrein-related peptidase 4 (Klk4) during pH cycling process. FASEB J. 2023 Apr;37(4):e22861
• All: 1 reference(s)