Tg(Fap-cre)#Rkl
Transgene Detail
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Symbol: |
Tg(Fap-cre)#Rkl |
Name: |
transgene insertion, Raghu Kalluri |
MGI ID: |
MGI:7546824 |
Synonyms: |
FAP-Cre |
Transgene: |
Tg(Fap-cre)#Rkl Location: unknown
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Alliance: |
Tg(Fap-cre)#Rkl page
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Fap-cre)#Rkl expression driven by
1 gene
Transgene expression driven by:
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Mutation details: The transgenic construct contains a 5 kb sequence including the Fap (fibroblast activation protein) promoter and part of exon 1 inserted into the pORF-FAP-TK vector to replace the full coding sequence of the Herpes simplex virus thymidine kinase with a cre expression cassette. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:325566)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Fap
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:325566 McAndrews KM, et al., Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer. Cancer Discov. 2022 Jun 2;12(6):1580-1597 |
All: |
1 reference(s) |
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