Tg(Lyz1-cre/ERT2)#Ngao
Transgene Detail

Summary

• Symbol: Tg(Lyz1-cre/ERT2)#Ngao
• Name: transgene insertion, Nan Gao
• MGI ID: MGI:7548470
• Synonyms: Lyz1^3'UTR-CreER
• Transgene: Tg(Lyz1-cre/ERT2)#Ngao Location: unknown
• Alliance: Tg(Lyz1-cre/ERT2)#Ngao page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Lyz1-cre/ERT2)#Ngao expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lyz1 (MGI:96902)

• Mutation details: The modified RP23-92F3 BAC containing Lyz1-3'UTR-IRES-CreER was purified and injected into C57BL6/J embryos. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:342295)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lyz1 (mouse) Summary of all recombinase alleles driven by Lyz1. Comparative matrix view of recombinase activities Alliance mouse Lyz1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:342295 Balasubramanian I, et al., Infection and inflammation stimulate expansion of a CD74(+) Paneth cell subset to regulate disease progression. EMBO J. 2023 Nov 2;42(21):e113975
• All: 1 reference(s)