St18^em1(cre)Yili
Endonuclease-mediated Allele Detail

Summary

• Symbol: St18^em1(cre)Yili
• Name: suppression of tumorigenicity 18; endonuclease-mediated mutation 1, Ying Li
• MGI ID: MGI:7548490
• Synonyms: St18-Cre
• Gene: St18 Location: Chr1:6557455-6931164 bp, + strand Genetic Position: Chr1, 1.89 cM
• Alliance: St18^em1(cre)Yili page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• St18^em1(cre)Yili expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	St18 (MGI:2446700)

• Mutation details: Using the CRISPR/Cas9 system, the IRES-Cre sequence was inserted just after the endogenous STOP codon of the St18 gene. (J:341874)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	St18 (mouse) Summary of all recombinase alleles driven by St18. Comparative matrix view of recombinase activities Alliance mouse St18 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any St18 Mutation: 71 strains or lines available

References

• Original: J:341874 Zhou X, et al., Hyperexcited limbic neurons represent sexual satiety and reduce mating motivation. Science. 2023 Feb 24;379(6634):820-825
• All: 1 reference(s)