Tg(Tas2r143-cre/ERT2)#Soff
Transgene Detail

Summary

• Symbol: Tg(Tas2r143-cre/ERT2)#Soff
• Name: transgene insertion, Stefan Offermanns
• MGI ID: MGI:7548525
• Synonyms: Tas2r143-CreERT2
• Transgene: Tg(Tas2r143-cre/ERT2)#Soff Location: unknown
• Alliance: Tg(Tas2r143-cre/ERT2)#Soff page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Tas2r143-cre/ERT2)#Soff expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tas2r143 (MGI:2681310)

• Mutation details: The genomic sequence between the start codon of the Tas2r143 gene and the stop codon of the Tas2r126 gene (35.2 kb) on the BAC clone RP23-316O11 containing the Tas2r143 promoter was replaced by a cassette carrying the CreERT2 cDNA followed by a polyadenylation (pA) signal. Three lines were generated with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:341916)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tas2r143 (mouse) Summary of all recombinase alleles driven by Tas2r143. Comparative matrix view of recombinase activities Alliance mouse Tas2r143 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:341916 Liu S, et al., Members of Bitter Taste Receptor Cluster Tas2r143/Tas2r135/Tas2r126 Are Expressed in the Epithelium of Murine Airways and Other Non-gustatory Tissues. Front Physiol. 2017;8:849
• All: 1 reference(s)