Phrf1^em1Mscha
Endonuclease-mediated Allele Detail

Summary

• Symbol: Phrf1^em1Mscha
• Name: PHD and ring finger domains 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:7549295
• Synonyms: PHRF1^fl
• Gene: Phrf1 Location: Chr7:140808697-140842663 bp, + strand Genetic Position: Chr7, 86.53 cM
• Alliance: Phrf1^em1Mscha page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct inserted a loxP site upstream of exon 2 and downstream of exon 9. (J:294183)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Phrf1 Mutation: 73 strains or lines available

References

• Original: J:294183 Shih TW, et al., An important role of PHRF1 in dendritic architecture and memory formation by modulating TGF-beta signaling. Sci Rep. 2020 Jul 2;10(1):10857
• All: 2 reference(s)