Ldhc^em1(LDHC)Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ldhc^em1(LDHC)Osb
• Name: lactate dehydrogenase C; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:7550375
• Gene: Ldhc Location: Chr7:46510687-46527571 bp, + strand Genetic Position: Chr7, 30.6 cM
• Alliance: Ldhc^em1(LDHC)Osb page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence)
• Mutation: Insertion
• Ldhc^em1(LDHC)Osb expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  LDHC (3948)

  Ldhc	(MGI:96764)

• CRISPR-targeting inserted the human sequence at the translation initiation site of exon 2. (J:338086)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ldhc Mutation: 14 strains or lines available

References

• Original: J:338086 Iida-Norita R, et al., Generation of humanized LDHC knock-in mice as a tool to assess human LDHC-targeting contraceptive drugs. Andrology. 2023 Jul;11(5):840-848
• All: 1 reference(s)