Fibcd1^tm1Spte
Targeted Allele Detail

Summary

• Symbol: Fibcd1^tm1Spte
• Name: fibrinogen C domain containing 1; targeted mutation 1, Steven P Templeton
• MGI ID: MGI:7567874
• Gene: Fibcd1 Location: Chr2:31703302-31736017 bp, - strand Genetic Position: Chr2, 21.89 cM
• Alliance: Fibcd1^tm1Spte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:340107
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• A neomycin resistance gene replaced exon 2. (J:340107)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fibcd1 Mutation: 22 strains or lines available

References

• Original: J:340107 Bhattacharya S, et al., FIBCD1 Deficiency Decreases Disease Severity in a Murine Model of Invasive Pulmonary Aspergillosis. Immunohorizons. 2021 Dec 22;5(12):983-993
• All: 2 reference(s)