Maf^{tm1.1(cre)Uze}
Targeted Allele Detail

Summary

• Symbol: Maf^{tm1.1(cre)Uze}
• Name: MAF bZIP transcription factor; targeted mutation 1.1, University of Zurich
• MGI ID: MGI:7567957
• Synonyms: c-Maf^Cre
• Gene: Maf Location: Chr8:116429992-116433633 bp, - strand Genetic Position: Chr8, 62.61 cM
• Alliance: Maf^{tm1.1(cre)Uze} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:343535
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Recombinase)
• Mutations: Insertion, Intragenic deletion
• Maf^{tm1.1(cre)Uze} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Maf (MGI:96909)

• Mutation details: The targeting construct replaced the coding region of the gene with a Cre recombinase open reading frame followed by an FRT-flanked neomycin cassette. Flp-mediated recombination removed the neo cassette. (J:343535)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Maf (mouse) Summary of all recombinase alleles driven by Maf. Alliance mouse Maf gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Maf Mutation: 27 strains or lines available

References

• Original: J:343535 Frezel N, et al., c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy. Cell Rep. 2023 Mar 21;42(4):112295
• All: 1 reference(s)