Tg(Myh6-ANKRD1)#Camm
Transgene Detail

Summary

• Symbol: Tg(Myh6-ANKRD1)#Camm
• Name: transgene insertion, Marina Campione
• MGI ID: MGI:7571599
• Transgene: Tg(Myh6-ANKRD1)#Camm Location: unknown
• Alliance: Tg(Myh6-ANKRD1)#Camm page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-ANKRD1)#Camm expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ANKRD1 (27063)

  Ankrd1

  (MGI:1097717)

• Mutation details: A 5kb Myh6 promoter drives expression of a human ANKRD1-FLAG tagged cDNA. Western blot and immunofluorescence analysis detected modest levels of expression in E10.5 and E14.5 hearts but higher levels of expression in neonatal and 10 month old hearts. Two lines, A and B, were generated. This record represents either pooled or unidentified lines. (J:302922)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:302922 Piroddi N, et al., Myocardial overexpression of ANKRD1 causes sinus venosus defects and progressive diastolic dysfunction. Cardiovasc Res. 2020 Jul 1;116(8):1458-1472
• All: 1 reference(s)