Fto^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fto^em1Cya
• Name: FTO alpha-ketoglutarate dependent dioxygenase; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7573097
• Synonyms: Fto^em1C
• Gene: Fto Location: Chr8:92040153-92395067 bp, + strand Genetic Position: Chr8, 44.34 cM
• Alliance: Fto^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting generated a knock-out allele. (J:344162)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fto Mutation: 71 strains or lines available

References

• Original: J:344162 Zhang J, et al., TWIK-related acid-sensitive K(+) channel 2 promotes renal fibrosis by inducing cell-cycle arrest. iScience. 2022 Dec 22;25(12):105620
• All: 1 reference(s)