Fgfr1^tm15.1Sor
Targeted Allele Detail

Summary

• Symbol: Fgfr1^tm15.1Sor
• Name: fibroblast growth factor receptor 1; targeted mutation 15.1, Philippe Soriano
• MGI ID: MGI:7575769
• Synonyms: Fgfr1^FCPGMyc
• Gene: Fgfr1 Location: Chr8:26008808-26067819 bp, + strand Genetic Position: Chr8, 14.12 cM
• Alliance: Fgfr1^tm15.1Sor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Epitope tag)
• Mutations: Insertion, Nucleotide substitutions
• Mutation details: A set of 5 point mutations were introduced to the mouse Fgfr1 gene via homologous recombination: L423A and V429A in exon 8, Y463F in exon 9, Y766F in exon 17, and Y776F in exon 17. An in-frame 2xMyc epitope tag was placed at the 3' end of the last exon. Cre-mediated recombination removed a loxP-flanked neomycin cassette in exon 8. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgfr1 Mutation: 221 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)