Tg(Thy1-APPSwe,-MAPT*P301L,-PSEN1*M146V)17Gpt
Transgene Detail
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Symbol: |
Tg(Thy1-APPSwe,-MAPT*P301L,-PSEN1*M146V)17Gpt |
Name: |
transgene insertion 17, GemPharmatech |
MGI ID: |
MGI:7576549 |
Synonyms: |
Tg(Thy-APP/Thy-PSEN1/Thy-MAPT)17 |
Transgene: |
Tg(Thy1-APPSwe,-MAPT*P301L,-PSEN1*M146V)17Gpt Location: unknown
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Alliance: |
Tg(Thy1-APPSwe,-MAPT*P301L,-PSEN1*M146V)17Gpt page
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Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Thy1-APPSwe,-MAPT*P301L,-PSEN1*M146V)17Gpt expresses
2 genes
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
APP (351) |
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human |
PSEN1 (5663) |
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Tg(Thy1-APPSwe,-MAPT*P301L,-PSEN1*M146V)17Gpt expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Thy1 (MGI:98747) |
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Mutation details: The transgene contains the Thy1 promoter driving expression of the human APP with the Sweden mutation, MAPT with the P301L mutation, and PSEN1 with mutation M146V.
(J:293217)
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Inheritance: |
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Not Specified |
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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