Alkal2^tm1Schl
Targeted Allele Detail

Summary

• Symbol: Alkal2^tm1Schl
• Name: ALK and LTK ligand 2; targeted mutation 1, Joseph Schlessinger
• MGI ID: MGI:7578836
• Synonyms: AugalphaGFP
• Gene: Alkal2 Location: Chr12:30934323-30943855 bp, + strand Genetic Position: Chr12, 13.0 cM
• Alliance: Alkal2^tm1Schl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:324631
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• A GFP gene was inserted to replace exons 1-4 of the endogenous coding region. (J:324631)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Alkal2 Mutation: 15 strains or lines available

References

• Original: J:324631 Ahmed M, et al., A hypothalamic pathway for Augmentor alpha-controlled body weight regulation. Proc Natl Acad Sci U S A. 2022 Apr 19;119(16):e2200476119
• All: 1 reference(s)