Ier3ip1^tm1Arvn
Targeted Allele Detail

Summary

• Symbol: Ier3ip1^tm1Arvn
• Name: immediate early response 3 interacting protein 1; targeted mutation 1, Peter Arvan
• MGI ID: MGI:7578873
• Synonyms: IER3IP1 floxed
• Gene: Ier3ip1 Location: Chr18:77017723-77029310 bp, + strand Genetic Position: Chr18, 51.98 cM
• Alliance: Ier3ip1^tm1Arvn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:336782
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• The mutation is an insertion of two loxP sites flanking exon 1. (J:336782)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ier3ip1 Mutation: 14 strains or lines available

References

• Original: J:336782 Yang J, et al., IER3IP1 is critical for maintaining glucose homeostasis through regulating the endoplasmic reticulum function and survival of beta cells. Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2204443119
• All: 1 reference(s)