Ints15^em2Takas
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ints15^em2Takas
• Name: integrator complex subunit 15; endonuclease-mediated mutation 2, Shuji Takada
• MGI ID: MGI:7578877
• Synonyms: Ints15^exon2
• Gene: Ints15 Location: Chr5:143286950-143301115 bp, - strand Genetic Position: Chr5, 82.07 cM
• Alliance: Ints15^em2Takas page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to generate a 7-bp deletion in exon 2. (J:337973)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ints15 Mutation: 17 strains or lines available

References

• Original: J:337973 Azuma N, et al., Integrator complex subunit 15 controls mRNA splicing and is critical for eye development. Hum Mol Genet. 2023 Jun 5;32(12):2032-2045
• All: 1 reference(s)