Rr79^em2Rtew
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr79^em2Rtew
• Name: regulatory region 79; endonuclease-mediated mutation 2, Ryan Tewhey
• MGI ID: MGI:7580428
• Synonyms: Bach2^18del
• Gene: Rr79 Location: unknown Genetic Position: Chr4, Syntenic
• Alliance: Rr79^em2Rtew page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This CRISPR/cas9-mediated mutation has an 18 bp deletion of Chr4:32,350,807-32,350,824 (mm9) that includes rs72928038 and the conserved region around it within the Bach2 intronic sequence (J:332957)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rr79 Mutation: 1 strain or line available

References

• Original: J:332957 Mouri K, et al., Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells. Nat Genet. 2022 May;54(5):603-612
• All: 1 reference(s)