Dync2i1^{Tn(pb-Act-RFP)1.1Zhu}
Transposon induced Allele Detail

Summary

• Symbol: Dync2i1^{Tn(pb-Act-RFP)1.1Zhu}
• Name: dynein 2 intermediate chain 1; transposon insertion 1.1, Yuan Zhuang
• MGI ID: MGI:7580876
• Synonyms: Wdr60^PB
• Gene: Dync2i1 Location: Chr12:116169882-116226642 bp, - strand Genetic Position: Chr12, 62.65 cM
• Alliance: Dync2i1^{Tn(pb-Act-RFP)1.1Zhu} page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Transposon induced (Null/knockout)
• Mutation: Transposon insertion
• Mutation details: The transposon containing an unspecified hybrid actin promoter driving expression of red fluorescent protein (RFP) flanked by piggyBac-specific left and right terminal sequences was co-injected with a piggyBac-containing transgene to mobilize the transposon. The transposon DNA fragment containing RFP sequence was inserted between exon 4 and 5 of gene. (J:123680, J:335806)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dync2i1 Mutation: 65 strains or lines available

References

• Original: J:335806 Yan L, et al., Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos. Front Cell Dev Biol. 2023;11:1084245
• All: 3 reference(s)