Rn4.5s^tm1.1Shna
Allele Detail

Summary

• Symbol: Rn4.5s^tm1.1Shna
• Name: 4.5S RNA; targeted mutation 1.1, Shinichi Nakagawa
• MGI ID: MGI:7581007
• Synonyms: 4.5SH KO
• Gene: Rn4.5s Location: Chr6:47631855-47632028 bp, - strand Genetic Position: Chr6, 22.94 cM
• Alliance: Rn4.5s^tm1.1Shna page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:344073
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6NJcl

Mutation description

• Allele Type: Not Applicable (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The floxed neomycin resistance cassette replaced the cluster. Cre-mediated recombination removed the selection cassette. (J:344073)

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rn4.5s Mutation: 0 strains or lines available

Notes

ES cells = 6NK7 (C57BL/6N Nippon Clea)

References

• Original: J:344073 Yoshimoto R, et al., 4.5SH RNA counteracts deleterious exonization of SINE B1 in mice. Mol Cell. 2023 Dec 21;83(24):4479-4493.e6
• All: 1 reference(s)