Myo3btm1Pgg
Targeted Allele Detail
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| Symbol: |
Myo3btm1Pgg |
| Name: |
myosin IIIB; targeted mutation 1, Peter G Gillespie |
| MGI ID: |
MGI:7581078 |
| Synonyms: |
Myo3b- |
| Gene: |
Myo3b Location: Chr2:69869470-70259542 bp, + strand Genetic Position: Chr2, 41.05 cM
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| Alliance: |
Myo3btm1Pgg page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:236347
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Conventional gene targeting eliminated exons 3 and 4, replacing them with a neomycin-resistance gene cassette conjugated to LacZ. A premature stop codon was introduced in exon 5. RT-PCR analysis of inner-ear mRNA demonstrated the expected truncated band in homozygous mutant mice.
(J:236347)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Myo3b Mutation: |
86 strains or lines available
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| Original: |
J:236347 Ebrahim S, et al., Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like. Nat Commun. 2016 Mar 01;7:10833 |
| All: |
1 reference(s) |
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Analysis Tools
