Ano9^em1.1Uoh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ano9^em1.1Uoh
• Name: anoctamin 9; endonuclease-mediated mutation 1, Uhtaek Oh
• MGI ID: MGI:7581980
• Gene: Ano9 Location: Chr7:140681125-140697719 bp, - strand Genetic Position: Chr7, 86.37 cM
• Alliance: Ano9^em1.1Uoh page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-cas9 mediated recombination inserted loxP sites in introns 7-8 and 9-10. Cre mediated recombination removed the floxed region. Immunoreactivity assays confirmed the absence of expression in olfactory epithelium from homozygous mice. (J:344977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ano9 Mutation: 41 strains or lines available

References

• Original: J:344977 Kim H, et al., Amplification of olfactory signals by Anoctamin 9 is important for mammalian olfaction. Prog Neurobiol. 2022 Dec;219:102369
• All: 1 reference(s)