Cfap119^em2Gaof
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cfap119^em2Gaof
• Name: cilia and flagella associated protein 119; endonuclease-mediated mutation 2, Fei Gao
• MGI ID: MGI:7594037
• Synonyms: Ccdc189-EGFP
• Gene: Cfap119 Location: Chr7:127182527-127187819 bp, - strand Genetic Position: Chr7, 69.61 cM
• Alliance: Cfap119^em2Gaof page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 genome editing technology was used to insert an EGFP coding sequence in-frame into exon 9 at the sequences encoding the C-terminus of the encoded protein. The EGFP tag did not affect the functions of the encoded protein. (J:345163)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cfap119 Mutation: 14 strains or lines available

References

• Original: J:345163 Wang M, et al., CCDC189 affects sperm flagellum formation by interacting with CABCOCO1. Natl Sci Rev. 2023 Sep;10(9):nwad181
• All: 1 reference(s)