Bcl2l13^em1Lrsn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Bcl2l13^em1Lrsn
• Name: BCL2 like 13; endonuclease-mediated mutation 1, Nils-Goran Larsson
• MGI ID: MGI:7594050
• Gene: Bcl2l13 Location: Chr6:120813173-120869803 bp, + strand Genetic Position: Chr6, 57.01 cM
• Alliance: Bcl2l13^em1Lrsn page

Mutation origin

• Strain of Origin: C57BL/6NCrl

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing technology was used to generate a 108 bp deletion (g.34512_34619del, g.120847678_120847785del, NCBI Reference Sequence: NC_000072.6). (J:345168)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl2l13 Mutation: 37 strains or lines available

References

• Original: J:345168 Kremer LS, et al., A role for BCL2L13 and autophagy in germline purifying selection of mtDNA. PLoS Genet. 2023 Jan;19(1):e1010573
• All: 1 reference(s)