Tspan15em1Psf
Endonuclease-mediated Allele Detail
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| Symbol: |
Tspan15em1Psf |
| Name: |
tetraspanin 15; endonuclease-mediated mutation 1, Paul Saftig |
| MGI ID: |
MGI:7594194 |
| Gene: |
Tspan15 Location: Chr10:62021175-62067030 bp, - strand Genetic Position: Chr10, 32.36 cM
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| Alliance: |
Tspan15em1Psf page
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| Allele Type: |
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Endonuclease-mediated (Null/knockout) |
| Mutation: |
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Intragenic deletion
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Mutation details: TALEN-mediated genome editing technology was used to generate a 104 bp deletion mutation inducing a translational stop codon in exon 2 of the gene. Immunoblot analysis confirmed the absence of protein in various tissues, including brain, heart, lung, spleen, kidney and liver.
(J:345187)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Tspan15 Mutation: |
12 strains or lines available
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| Original: |
J:345187 Seipold L, et al., In vivo regulation of the A disintegrin and metalloproteinase 10 (ADAM10) by the tetraspanin 15. Cell Mol Life Sci. 2018 Sep;75(17):3251-3267 |
| All: |
1 reference(s) |
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Analysis Tools
