Efr3b^tm1Gpt
Targeted Allele Detail

Summary

• Symbol: Efr3b^tm1Gpt
• Name: EFR3 homolog B; targeted mutation 1, GemPharmatech
• MGI ID: MGI:7594220
• Gene: Efr3b Location: Chr12:4012554-4088915 bp, - strand Genetic Position: Chr12, 1.99 cM
• Alliance: Efr3b^tm1Gpt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:344437
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4 and a loxP site and frt-flanked pgk-neo cassette were inserted downstream of exon 8 via homologous recombination (J:344437)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Efr3b Mutation: 27 strains or lines available

References

• Original: J:344437 Wei X, et al., Efr3b is essential for social recognition by modulating the excitability of CA2 pyramidal neurons. Proc Natl Acad Sci U S A. 2024 Jan 16;121(3):e2314557121
• All: 1 reference(s)