Ahdc1^em#Oro
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ahdc1^em#Oro
• Name: AT hook, DNA binding motif, containing 1; endonuclease-mediated mutation 1, Anthony E Oro
• MGI ID: MGI:7595527
• Gene: Ahdc1 Location: Chr4:132738797-132805421 bp, + strand Genetic Position: Chr4, 66.18 cM
• Alliance: Ahdc1^em#Oro page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• Mutation details: Pronuclear CRISPR injections targeting the coding exon generated mosaic genotypes that exhibit CRISPR cutting on at least one allele. (J:326009)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ahdc1 Mutation: 211 strains or lines available

References

• Original: J:326009 Collier A, et al., Gibbin mesodermal regulation patterns epithelial development. Nature. 2022 Jun;606(7912):188-196
• All: 1 reference(s)