Cxcl11^m1
Spontaneous Allele Detail

Summary

• Symbol: Cxcl11^m1
• Name: chemokine (C-X-C motif) ligand 11; mutation 1
• MGI ID: MGI:7596095
• Gene: Cxcl11 Location: Chr5:92507403-92511155 bp, - strand Genetic Position: Chr5, 46.61 cM, cytoband E3
• Alliance: Cxcl11^m1 page

Mutation origin

• Strain of Origin: C57BL/6ByJ

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutations: Intragenic deletion, Single point mutation
• Mutation details: The C57BL/6ByJ sequence was identical to that of C57BL/6 (NR_038116). Both strains have genomic sequences that contains a G to A substitution and single cytosine nucleotide deletion at positions 99 and 102, respectively, of the Balb/c reference sequence (Fig. 2d). The single base pair deletion is predicted to result in a frameshift mutation and production of a truncated version of the protein. (J:319051)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cxcl11 Mutation: 6 strains or lines available

References

• Original: J:319051 Qi Z, et al., Listr1 locus regulates innate immunity against Listeria monocytogenes infection in the mouse liver possibly through Cxcl11 polymorphism. Immunogenetics. 2014 Apr;66(4):231-42
• All: 2 reference(s)