Cxxc4^em1Mmda
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cxxc4^em1Mmda
• Name: CXXC finger 4; endonuclease-mediated mutation 1, Meelad M Dawlaty
• MGI ID: MGI:7606855
• Synonyms: Idax^-
• Gene: Cxxc4 Location: Chr3:133942245-133967922 bp, + strand Genetic Position: Chr3, 62.12 cM
• Alliance: Cxxc4^em1Mmda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:344836
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exon 3. (J:344836)

Expression

In Mice Carrying this Mutation:

15 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxxc4 Mutation: 13 strains or lines available

References

• Original: J:344836 Abou-Jaoude A, et al., Idax and Rinf facilitate expression of Tet enzymes to promote neural and suppress trophectodermal programs during differentiation of embryonic stem cells. Stem Cell Res. 2022 May;61:102770
• All: 1 reference(s)