Eogt^tm1.1Okaj
Targeted Allele Detail

Summary

• Symbol: Eogt^tm1.1Okaj
• Name: EGF domain specific O-linked N-acetylglucosamine transferase; targeted mutation 1.1, Tetsuya Okajima
• MGI ID: MGI:7607995
• Synonyms: Eogt^F
• Gene: Eogt Location: Chr6:97086985-97126143 bp, - strand Genetic Position: Chr6, 44.88 cM
• Alliance: Eogt^tm1.1Okaj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:254752
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 10 and a loxP/FRT-flanked neomycin selection cassette was inserted downstream of exon 10. The neomycin selection cassette was removed via flp-mediated recombination, leaving exon 10 floxed. (J:254752)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Eogt Mutation: 44 strains or lines available

References

• Original: J:254752 Sawaguchi S, et al., O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals. Elife. 2017 Apr 11;6:e24419
• All: 1 reference(s)