Or55b4^em1Lsj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Or55b4^em1Lsj
• Name: olfactory receptor family 55 subfamily B member 4; endonuclease-mediated mutation 1, Sung-Joon Lee
• MGI ID: MGI:7608095
• Gene: Or55b4 Location: Chr7:102133321-102137514 bp, - strand Genetic Position: Chr7, 54.73 cM
• Alliance: Or55b4^em1Lsj page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 mediated recombination using guide RNAs targeting exon 2 created a 268 bp deletion spanning positions 161-428. (J:252600)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Or55b4 Mutation: 13 strains or lines available

References

• Original: J:252600 Wu C, et al., Olfactory receptor 544 reduces adiposity by steering fuel preference toward fats. J Clin Invest. 2017 Nov 1;127(11):4118-4123
• All: 2 reference(s)