Cep55^em1.1Hyli
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cep55^em1.1Hyli
• Name: centrosomal protein 55; endonuclease-mediated mutation 1.1, Hui-Yan Li
• MGI ID: MGI:7608263
• Gene: Cep55 Location: Chr19:38043459-38062871 bp, + strand Genetic Position: Chr19, 32.69 cM, cytoband C3
• Alliance: Cep55^em1.1Hyli page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The loxP-flanked exons 3-5 were deleted via cre-mediated recombination, resulting in a frame-shift. Western blot analysis confirmed absence of protein in mouse embryonic fibroblasts. (J:313163)

Disease models

Expression

In Structures Affected by this Mutation:

10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cep55 Mutation: 71 strains or lines available

References

• Original: J:313163 Zhang YC, et al., CEP55 promotes cilia disassembly through stabilizing Aurora A kinase. J Cell Biol. 2021 Feb 1;220(2)
• All: 1 reference(s)