Mical1^tm1.1Past
Targeted Allele Detail

Summary

• Symbol: Mical1^tm1.1Past
• Name: microtubule associated monooxygenase, calponin and LIM domain containing 1; targeted mutation 1.1, Jeroen Pasterkamp
• MGI ID: MGI:7610556
• Synonyms: MICAL-1^fl
• Gene: Mical1 Location: Chr10:41352310-41363028 bp, + strand Genetic Position: Chr10, 22.41 cM
• Alliance: Mical1^tm1.1Past page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:240378
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site and FRT site flanked neomycin resistance gene cassette were inserted in intron 1 and a second loxP site was inserted in intron 3. The neo cassette was removed via Flp-mediated recombination leaving exons 1-3 floxed. (J:240378)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mical1 Mutation: 50 strains or lines available

References

• Original: J:240378 Van Battum EY, et al., The intracellular redox protein MICAL-1 regulates the development of hippocampal mossy fibre connections. Nat Commun. 2014 Jul 10;5:4317
• All: 1 reference(s)