Tor1aip2^tm1.1Wtd
Targeted Allele Detail

Summary

• Symbol: Tor1aip2^tm1.1Wtd
• Name: torsin A interacting protein 2; targeted mutation 1.1, William T Dauer
• MGI ID: MGI:7610710
• Synonyms: LUL-flox, Tor1aip2^fl
• Gene: Tor1aip2 Location: Chr1:155911410-155944607 bp, + strand Genetic Position: Chr1, 67.7 cM, cytoband G3
• Alliance: Tor1aip2^tm1.1Wtd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:345574
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J x 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT-flanked neo cassette and loxP site were inserted downstream of exon 4 via homologous recombination. Flp-mediated recombination removed the neo cassette. (J:345574)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tor1aip2 Mutation: 97 strains or lines available

References

• Original: J:345574 Hernandez-Ono A, et al., Dynamic regulation of hepatic lipid metabolism by torsinA and its activators. JCI Insight. 2024 Jan 9;:e175328
• All: 1 reference(s)